Mac OS X applications that print using the standard system print dialog should be able to take advantage of the system's ability to easily generate PDF files.

1. From within the application, select Print from the File menu. 

2. Instead of choosing Print, choose the PDF menu from the bottom-left of the print dialog. Select Save as PDF...

3. Select what you would like to name the PDF file, as well as select where you would like to save the file on your Mac. 

4. You can now open the PDF file you have saved in your preferred PDF viewing application (such as Preview, Adobe Reader, or Adobe Acrobat Pro).